While on the run from the police, an unlikely companionship blossoms between a funny con man who just broke out of jail, the bumbling cop whose car he seized at gunpoint, and a nitpicking civilian he unwittingly took hostage.
This time the "amici" (friends) are just four: Necchi, Meandri, Mascetti and Sassaroli. Nevertheless they are older they still love to spend their time mainly organizing irresistible jokes to everyone in every kind of situation. Mascetti is hospitalized in a geriatric clinic. Of course the place become immediately the main stage for all their jokes. After some jokes they decided to place an ultimate incredible and farcical joke to the clinic guests.
Advertising executive Nick Beame learns that his wife is sleeping with his employer. In a state of despair, he encounters a bumbling thief whose attempted carjacking goes awry when Nick takes him on an involuntary joyride. Soon the betrayed businessman and the incompetent crook strike up a partnership and develop a robbery-revenge scheme. But it turns out that some other criminals in the area don't appreciate the competition.
Detective Guy Johnson's client, Willie Heywood, is framed for murder. While Guy hides him so he can catch the real killer, both of them are nabbed by the police, tried, convicted and sentenced to jail: Guy for a year with Willie to be executed. On the way to jail, Guy comes across a clue and escapes from the police.
Mexican aviation exec Renato is shocked to learn that he has an American half-brother he never knew about: free-spirited Asher. They are forced on a road trip together, tracing the path their father took from Mexico to the U.S.
Restless and ready for an adventure, four suburban bikers leave the safety of their subdivision and head out on the open road. But complications ensue when they cross paths with an intimidating band of New Mexico bikers known as the Del Fuegos.
Ana meets Rafa in a chance encounter and they embark on a road trip to try and save him from bankruptcy, or worse.
After their high school basketball coach passes away, five good friends and former teammates reunite for a Fourth of July holiday weekend.
A bumbling tramp desires to build a home with a young woman, yet is thwarted time and time again by his lack of experience and habit of being in the wrong place at the wrong time..
Successful movie director John L. Sullivan, convinced he won't be able to film his ambitious masterpiece until he has suffered, dons a hobo disguise and sets off on a journey, aiming to "know trouble" first-hand. When all he finds is a train ride back to Hollywood and a beautiful blonde companion, he redoubles his efforts, managing to land himself in more trouble than he bargained for when he loses his memory and ends up a prisoner on a chain gang.
When recently single Steven moves into his new apartment, cable guy Chip comes to hook him up—and doesn't let go. Initially, Chip is just overzealous in his desire to be Steven's pal, but when Steven tries to end the 'friendship', Chip shows his dark side. He begins stalking Steven, who's left to fend for himself because no one else can believe Chip's capable of such behaviour.
As his wedding day approaches, Ben heads to Miami with his soon-to-be brother-in-law James to bring down a drug dealer who's supplying the dealers of Atlanta with product.
Down-on-their-luck racers Larry and Deke steal from a supermarket manager to buy a car that will help them advance their racing chances. Their escape does not go as planned when Larry's one-night stand, Mary, tags along for the ride.
Frank Drebin is persuaded out of retirement to go undercover in a state prison. There he has to find out what top terrorist, Rocco, has planned for when he escapes. Adding to his problems, Frank's wife, Jane, is desperate for a baby.
The four old friends meet on the grave of the fifth of them, Perozzi, who died at the end of the first episode. Time has passed but they are still up for adventures and cruel jokes, and while they recall the one they created together with the late friend, new ones are on their way, starting right there at the cemetery.
After Doug picks up hitchhiking Rosco with his truck, they are mistaken for two bank robbers by the traffic police. They manage to escape only to be confused for two secret agents while trying to take a flight at the airport.
Al Fountain, a middle-aged electrical engineer, is on the verge of a mid-life crisis, when he decides to take his time coming home from a business trip, rents a car, and heads out looking for a lake he remembers from his childhood. But his wandering takes him into the life of Kid, a free-spirited young man who helps Al escape from the routine of everyday life and find freedom to enjoy himself.
On his first day after being released from jail for 14 armed bank robberies, Lucas finds himself caught up in someone else's robbery. Perry has decided to hold up the local bank to raise money so that he can keep his daughter, Meg, and get her the treatment she needs. Dugan, a detective, assumes Lucas helped plan the robbery, and hence Lucas, Perry and Meg become three fugitives.
Will is looking for an escape from his family when he encounters Lee, the school bully. Armed with a video camera and a copy of Rambo, Lee plans to make his own action-packed video epic.
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