Concern for her father, who is being slowly ruined by cattle rustling, prompts Mary Benson to do some investigating in a distant cattle town, where she briefly encounters drifters Oklahoma Adams and Sneezer Clark. They follow her back to Arizona, go to work on the Benson ranch, and discover the ranch foreman to be responsible for the rustling and the robbery of a rodeo box office.
Traveling north into Arizona, Cisco finds that someone committing robberies has been impersonating him and he is a wanted man. After retrieving some of the stolen loot, he is caught with it in his posession and put in the guard house. A friend whose life he recently saved beaks him out and Cisco heads out to find the impersonator and clear himself.
A drunken gunfighter, Ben Walker, is one day visited by an old friend's daughter who needs his help. The gold digger Tom is being chased by a gang of bandits and heads to Carson City. He gives his daughter Isabella his treasure map and tells her that she need find his old friend Ben and let him help her to locate the hidden gold.
In this western, a cowboy and his pals must stop outlaws from stealing a cache of gold ore. Action ensues, and they succeed.
Chester Carr, owner of a dude ranch in the Rockies, caters to guests seeking the thrill of the Wild West. Among his guests are the wealthy Spruce Meadows and his daughter Susan. But the West isn't wild anymore and most of Carr's guests are bored and about to leave. He is in despair when a caravan carrying a broke-down-and-out troupe of actors---Jennifer, Judd, Mrs. Merridew and her daughter, Alice---crashes down the hill and wrecks the hotel sign.
Nugget, Underwood and Short walk to the Half-Way House after the driver purposely wrecks the stage. They arrive late at night and it is so spooky that Nugget leaves for Amarillo. Unknown to him, the dead body of Short is in the wagon. When Sheriff Lane comes upon Nugget and the body, he goes to investigate and finds no trace of Underwood at all. But he soon finds that Underwood was carrying $50,000 in cash and he believes the story Nugget is telling.
At a trading post in the Northern Dakotas, Hawk Lespard, an unscrupulous trader, is opposed by Jack Jessup, posing as a gambler but actually a scout for the Overland Stage Co., and Kunga-Sunga, a wizard with the lariat.
A nobleman returns home to Southern California after the Mexican American War to find his people mistreated by unscrupulous Americans.
Redwood Valley residents raise $50,000 for blasting a mountain tunnel to bring a new railroad there. Town leader Bidwell engineers a plot to steal the money and to blame it on the Reno Kid (Bob Steele) who has recently broken out of prison in order to clear himself of false charges that sent him there and caused him to lose his ranch. The badly-wounded sheriff turns his badge over to Red Ryder. Reno visits his wife, Molly and their ailing son Johnny, and Red, also wounded, is brought there by Little Beaver. There, Red begins to believe Reno's story about being innocent. Written by Les Adams
Johnny Texas is asked to inquire about the death of Prescott, a rich landowner accused of having robbed a postal wagon. His investigation upsets Prescott's neighbor, Martin, who will use all possible means to stop him.
Sintown is just a deserted ghost town until Vanerpool starts looking for silver. Cookie and Roy's partners put $20,000 into the business only to find that the mine is worthless and Vanerpool is bankrupt. Carol comes out to look for silver to save the company, but does not know that their engineer, named Regan, is crooked and wants all the silver for himself. But only Old Ed knows where the mother lode is located.
A young man and his trusty dog go up against a gang of crooks that are building a dam out of shoddy materials, which could collapse and flood the entire valley.
A lumber man called the Timber Wolf comes to the aid of an old prospector.
After Jim Blake saves Harve Tarlton's life, they become partners in a gold mining claim. After a while Harve reverts to his outlaw way of life. Everyone but Jim seems to know that Harve is bad but Jim merely thinks he needs a chance to go straight. But Jim's wife Helen has a plan to expose Harve as the outlaw he is.
A sinister town boss called Pat Barnes has exploited almost everyone in the town. If they don't succumb to his demands they normally end up dead. Barnes is finally brought down by Shanghai Joe and a smooth-talking snake-oil salesman.
Bud Harris, who is in love with Molly Vernon, leaves the Vernon ranch when there is an oil boom in the territory, then returns to find the property encumbered with debt. Bush, who holds the mortgage on the ranch, attempts to foreclose when he learns that there is oil on the land, and Bud enters a horserace to pay the debt.
During the War of Independence, a group of Southern soldiers form an alliance with the Apache Indians for the purpose of hunting down and killing the Northern soldiers stationed at Fort Worth.
Outlaws of the Pandhandle was the last of Charles Starrett's "formula" westerns for Columbia: hereafter, Starrett would be seen only in the guise of frontier medico Steven Monroe or masked do-gooder The Durango Kid. For the moment, however, the star is cast as Jim Endicott, bound and determined to put an end to the underhanded activities of gin-mill operator Faro Jack Vaughn (Norman Willis). The villain's strategy is to get the local cowpunchers tanked up on rotgut that they'll prove to be easy pickings for a gang of rustlers-and will be unable to complete work on a railroad spur which will bypass the outlaws' hideaway.
An Easterner Inherits a cattle ranch, only to discover that thousands of cattle have been stolen. He secretly signs on as a hired hand at his own ranch to discover who's stealing them.
Larrabie Keller, a homesteader, is accused of being a cattle rustler, and when Keller refuses to fight Phil Sanderson, whose sister, Phyllis, has struck his fancy, he is insulted by Bill Healy, to whom he administers a severe drubbing. Phyllis, finding Keller beside a branding fire, believes him guilty; and when he is wounded by Healy, she takes Keller to Yeager, another homesteader, who cares for him and to whom he reveals that he is a Texas Ranger.
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